Browsing by Author "Hermoso Ramello, Marcela"

Now showing items 1-19 of 19

    • Alterations in Type I Hemidesmosome Components Suggestive of Epigenetic Control in the Salivary Glands of ... 
      González, Sergio; Aguilera, Sergio; Alliende, Cecilia; Urzúa Tobar, Ulises; Quest, Andrew F. G.; Herrera Cisterna, Luisa; Molina, Claudio; Hermoso Ramello, Marcela; Ewert, Patricia; Brito, Mónica; Romo, Rafael; Leyton Martínez, Cecilia; Pérez, Paola; González Burgos, María Julieta (2011-04)
      Objective. Acinar cells in the salivary glands of patients with Sjo¨gren’s syndrome (SS) display severe alterations in anchorage to the basal lamina. Bioinformatics analysis of the BP230 gene sequence has revealed the ...
    • Caracterización de las variantes del receptor tipo TOLL (TLR2) humano en las enfermedades inflamatorias ... 
      Farfán Troncoso, Nancy María (Universidad de Chile, 2012)
      Las enfermedades inflamatorias intestinales (EII) se caracterizan por presentar una respuesta inmune intestinal exagerada frente a los antígenos de la dieta o a la microbiota. Entre las EII destacan la colitis ulcerosa ...
    • Changes in Rab3D Expression and Distribution in the Acini of Sjogren's Syndrome Patients Are Associated ... 
      Bahamondes, Verónica; Albornoz, Amelina; Aguilera, Sergio; Alliende, Cecilia; Molina, Claudio; Castro, Isabel; Urzúa Tobar, Ulises; Quest, Andrew F. G.; Barrera, María José; González, Sergio; Sánchez, Marianela; Härtel, Steffen; Hermoso Ramello, Marcela; Leyton Martínez, Cecilia; González Burgos, María Julieta (WILEY-BLACKWELL, 2011-10)
      Objective. Oral and ocular dryness are frequent and serious symptoms of Sjogren's syndrome (SS) that reflect problems in secretion due to glandular dysfunction. Exocytosis, an important process in the secretory pathway, ...
    • Changes in Rab3D expression and distribution in the acini of Sjögren's syndrome patients are associated ... 
      Bahamondes, Verónica; Albornoz, Amelina; Aguilera, Sergio; Alliende, Cecilia; Molina, Claudio; Castro, Isabel; Urzúa, Ulises; Quest, Andrew F. G.; Barrera, María José; González, Sergio; Sánchez, Marianela; Härtel, Steffen; Hermoso Ramello, Marcela; Leyton, Cecilia; González, Ma (2011)
      Objective Oral and ocular dryness are frequent and serious symptoms of Sjögren's syndrome (SS) that reflect problems in secretion due to glandular dysfunction. Exocytosis, an important process in the secretory pathway, ...
    • ClC-3 is a fundamental molecular component of volume-sensitive outwardly rectifying Cl- channels and volume ... 
      Hermoso Ramello, Marcela; Satterwhite, Christina M.; Andrade, Yaniré Naty; Segura Hidalgo, Jorge Antonio; Wilson, Sean M.; Horowitz, Burton; Hume, Joseph R. (2002)
      Volume-sensitive osmolyte and anion channels (VSOACs) are activated upon cell swelling in most vertebrate cells. Native VSOACs are believed to be a major pathway for regulatory volume decrease (RVD) through efflux of ...
    • Corrigendum to “Escherichia coli isolates from inflammatory bowel diseases patients survive in macrophages and ... 
      Fuente, Marjorie de la; Franchi, Luigi; Araya, Daniela; Díaz Jiménez, David; Olivares, Mauricio; Álvarez Lobos, Manuel; Golenbock, Douglas; González Burgos, María Julieta; López Kostner, Francisco; Quera Pino, Rodrigo; Núñez, Gabriel; Vidal Álvarez, Roberto; Hermoso Ramello, Marcela (ELSEVIER, 2015)
    • Decreased salivary sulphotransferase activity correlated with inflammation and autoimmunity parameters in ... 
      Castro, Isabel; Aguilera, Sergio; Brockhausen, Inka; Alliende, Cecilia; Quest, Andrew F. G.; Molina, Claudio; Urzúa Tobar, Ulises; Mandel, Ulla; Bahamondes, Verónica; Barrera, María José; Sánchez, Marianela; González, Sergio; Hermoso Ramello, Marcela; Leyton Martínez, Cecilia; González Burgos, María Julieta (Oxford University Press, 2012)
      Objectives. To determine the expression and enzymatic activities of sulphotransferases involved in mucin hyposulphation in labial salivary glands (LSGs) from SS patients and to correlate sulphotransferase activity with ...
    • Disruption of tight junction structure in salivary glands from Sjögren's syndrome patients is linked to ... 
      Ewert, Patricia; Aguilera, Sergio; Alliende, Cecilia; Kwon, Yoon Jeoung; Albornoz, Amelina; Molina, Claudio; Urzúa, Ulises; Quest, Andrew F. G.; Olea, Nancy; Pérez, Paola; Castro, Isabel; Barrera, María José; Romo, Rafael; Hermoso Ramello, Marcela; Leyton, Cecilia; González, Mar (2010)
      Objective. Disorganization of acinar cell apical microvilli and the presence of stromal collagen in the acinar lumen suggest that the labial salivary gland (LSG) barrier function is impaired in patients with Sjögren's ...
    • Estandarización de un elisa de captura para la medición de la forma soluble del receptor tipo toll 2 en ... 
      Carvajal Muñoz, Salvador (Universidad de Chile, 2009)
      Ios receptores tipo Toll (mts) son proteínas transmembrana capaces de unir patrones moleculares acostados a macroorganismos. ha activación de estos receptores conduce al desarrollo de la respuesta Inmune innata al ...
    • Estudio de la regulación de la vía esteroidogénica intestinal y su caracterización en pacientes con colitis ... 
      Bitrán Ambler, Mirit Luisa (Universidad de Chile, 2019)
      Las enfermedades inflamatorias del intestino (EII) son condiciones de inflamación crónica del tracto gastrointestinal y abarca dos manifestaciones clínicas principales: Enfermedad de Crohn (EC) y Colitis Ulcerosa (CU). En ...
    • Genetic diversity and virulence determinants of Escherichia coli strains isolated from patients with Crohn's ... 
      Céspedes, Sandra; Saitz Rojas, Waleska; Canto Fuentes, Felipe del; Fuente, Marjorie de la; Quera Pino, Rodrigo; Hermoso Ramello, Marcela; Muñoz, Raúl; Ginard, Daniel; Khorrami, Sam; Jorge, Girón; Assar Cuevas, Rodrigo; Rosello Mora, Ramón; Vidal Álvarez, Roberto (Frontiers Media, 2017)
      Adherent-invasive Escherichia coli (AIEC) strains are genetically variable and virulence factors for AIEC are non-specific. FimH is the most studied pathogenicity-related protein, and there have been few studies on other ...
    • Glucocorticoids impair phagocytosis and inflammatory response against crohn's disease-associated adherent-invasive ... 
      Olivares Morales, Mauricio; Fuente, Marjorie de la; Dubois Camacho, Karen; Palominos Parada, Daniela Paz; Díaz Jiménez, David; Torres Riquelme, Alejandro; Xu, Xiaojiang; Chamorro Veloso, Nayaret; Naves, Rodrigo; González Burgos, María Julieta; Quera Pino, Rodrigo; Figueroa, Carolina; Cidlowski, John Anthony; Vidal, Roberto; Hermoso Ramello, Marcela (Frontiers Media, 2018)
      Crohn's disease (CD) is a chronic inflammatory bowel disorder characterized by deregulated inflammation triggered by environmental factors Notably, adherent-invasive Escherichia coli (AIEC), a bacterium with the ability ...
    • IL-23R Arg381Gln polymorphism in Chilean patients with inflammatory bowel disease 
      Venegas Santos, Mauricio; Beltrán Muñoz, Caroll; Alvarez, Luis; Castro, Ariel; Torres, Tamara; Leal, Andrea D.; Lahsen, Francisca M.; Hermoso Ramello, Marcela; Quera Pino, Rodrigo (2008-12)
      Crohn’s disease (CD) and ulcerative colitis (UC) are multifactorial diseases with a genetic background. Recent results have shown that a non-synonymous, single nucleotide polymorphism (rs11209026, c.1142G>A, p.Arg381Gln) ...
    • Mechanotransduction and epigenetic control in autoimmune diseases 
      González, Sergio; Aguilera, Sergio; Urzúa Tobar, Ulises; Quest, Andrew F. G.; Molina, Claudio; Alliende, Cecilia; Hermoso Ramello, Marcela; González Burgos, María Julieta (Elsevier, 2011)
      Differentiation of epithelial cells is required to define tissue architecture and appropriate function of these cells is associated with a specific pattern of gene expression. DNA methylation, post-translational modification ...
    • MUC1/SEC and MUC1/Y overexpression is associated with inflammation in Sjögren's syndrome 
      Sung, H. H.; Castro, I.; González, S.; Aguilera, S.; Smorodinsky, N. I.; Quest, Andrew F. G.; Bahamondes, V.; Alliende, C.; Cortés, J.; Molina, C.; Urzúa, U.; Barrera, M. J.; Hermoso Ramello, Marcela; Herrera, L.; Leyton, C.; González, M. J. (Blackwell, 2015)
      ORIGINAL ARTICLEMUC1/SEC and MUC1/Y overexpression is associatedwith inflammation in Sj€ogren’s syndromeHH Sung1,*, I Castro1,*, S Gonz alez2, S Aguilera3, NI Smorodinsky4, AFG Quest1,5, V Bahamondes1,C Alliende1, J Cort ...
    • Oral dryness in Sjögren's syndrome patients. Not just a question of water 
      Castro, I.; Sepúlveda, D.; Cortés, J.; Quest, Andrew F. G.; Barrera, M. J.; Bahamondes, V.; Aguilera, S.; Urzúa Tobar, Ulises; Alliende, C.; Molina, C.; González, S.; Hermoso Ramello, Marcela; Leyton Blanca, Cristina; González, M. J. (Elsevier, 2013)
      Sjögren's syndrome (SS) is a chronic autoimmune disease of undefined etiology. Patients with this syndromesuffer from severe alterations in both the quality and quantity of saliva and tears, due to impaired function of ...
    • Pro-inflammatory cytokines enhance ERAD and ATF6 alpha pathway activity in salivary glands of Sjogren's ... 
      Barrera, María José; Aguilera, Sergio; Castro, Isabel; Cortés Araya, Juan Eliecer; Bahamondes Lorca, Verónica; Quest, Andrew F. G.; Molina, Claudio; González, Sergio; Hermoso Ramello, Marcela; Urzúa Tobar, Ulises; Leyton, Cecilia; González Burgos, María Julieta (Elsevier, 2016)
      Salivary gland (SG) acinar-cells are susceptible to endoplasmic reticulum (ER) stress related to their secretory activity and the complexity of synthesized secretory products. SGs of Sji5gren's syndrome patients (SS)-patients ...
    • Regulación de la respuesta de linfocitos T reguladores por Interferón-gamma en encefalomielitis autoinmune ... 
      Arellano Lorca, Gabriel Alejandro de Jesús (Universidad de Chile, 2017)
      La Esclerosis Múltiple (EM) es una enfermedad autoinmune y crónica que afecta al sistema nervioso central (SNC), caracterizada por una pérdida de la de tolerancia inmunológica, que incluye la inactivación funcional de ...
    • Salivary mucins induce a Toll-like receptor 4-mediated pro-inflammatory response in human submandibular ... 
      Barrera, María José; Aguilera, Sergio; Veerman, Enno; Quest, Andrew F. G.; Díaz Jiménez, David; Urzúa Tobar, Ulises; Cortés Araya, Juan Eliecer; González, Sergio; Castro, Isabel; Molina, Claudio; Bahamondes, Verónica; Leyton, Cecilia; Hermoso Ramello, Marcela; González Burgos, María Julieta (Oxford Univ Press, 2015)
      Objectives. A hallmark characteristic of SS patients is the ectopic presence of the mucins MUC5B and MUC7 in the extracellular matrix of salivary glands that have lost apical basolateral acinar-cell polarity. This study ...